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Derived from a combination of the anabolic steroid nandrolone (19-nortestosterone) and the androgen prohormone dehydroepiandrosterone (DHEA-5), 19-NoreDHEA converts back to nandrolone in the body. nandrolone is a hormone that is released from the pituitary gland and binds to androgen receptors, including ERα and ERβ. 20 The binding of nandrolone to androgen receptors is mediated by the epidermal growth factor receptor (EGFR). EGF-receptor activation promotes cell growth and development. 21 Therefore, 19-NoreDHEA could bind to androgen-sensitive receptors in the skin and promote angiogenesis. In addition, 19-NO plays an important role in angiogenesis. The end result of these binding relationships is increased blood flow to the skin and increased blood flow to muscle and joint. 22 22 A study from the laboratory of the German dermatological dermatologist Prof. Ernst Juhlin showed that nandrolone could be a potent agonist of the ERα and ERβ in cultured human skin keratinocytes. 24 19-NoreDHEA binds with affinity to norepinephrine and anandrogliptin receptors. 25 18 19 An association between nandrolone and increased arterial tension has been identified from a study on human volunteers. 26 The association between nitric oxide and vascular stiffness has been explored for the first time in human volunteers. 27 The association between blood pressure and the concentration of DHEA in the plasma also proved to be a unique relationship. 28 The present study investigated the association between nandrolone and endothelium-derived vasodilators (EDV) in the blood, specifically in the vasculature of the human heart. The human heart is the largest heart among mammals and is connected to an extensive network of blood vessels. The heart muscle contributes over 90% of total heart volume, and heart and pulmonary systolic blood pressure is highly correlated (r = 0.99, confidence interval [CI]) with the heart rate. The relationship between blood pressure and EDV in the human heart is similar to that between pulmonary systolic pressure and diastolic pressure and the relationship between pulmonary systolic pressure and cardiac index. 29 The cardiac index is a ratio of systolic-to-diastolic pressure which is used as a measure of cardiac resistance in the chest and a predictive factor for the future risk of heart attack. 30 In patients with coronary artery disease, cardiac index is associated with coronary artery disease mortality and coronary thrombotic disease. 31 The relationship between EDV and heart disease has also been investigated in the elderly. In a study of 1225 subjects, the Related Article:

High testosterone and psa levels, buy anabolic steroids online ireland
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